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1996-03-09
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Document 0522
DOCN M9650522
TI Seroprevalence and risk factors associated with HTLV-I/II infection in
injection drug users in northern New Jersey.
DT 9605
AU Freeman RC; Rodriguez GM; French JF; New Jersey State Department of
Health, Division of Alcoholism,; Drug Abuse, and Addiction Services,
Newark, USA.
SO J Addict Dis. 1995;14(3):51-66. Unique Identifier : AIDSLINE
MED/96127013
AB Data from an AIDS Demonstration Research project in Paterson, NJ, that
enrolled out-of-treatment injection drug users (IDUs) were analyzed to
detect demographic patterns and risk factors associated with infection
with human immunodeficiency virus (HIV) and human T-lymphotropic virus
types I or II (HTLV-I/II). Of 410 IDUs screened, 44.2% were HIV-positive
and 19.3% were HTLV-I/II-positive. African-Americans were significantly
more likely than other racial groups to be HTLV-I/II-seropositive and to
be HIV-seropositive. Over one-fifth of African-Americans--but no Latinos
or whites--were doubly infected with HIV and HTLV-I/II. In logistic
regression analysis, African-American race, long-term injection drug
use, and age were significant predictors of HTLV-I/II-seropositivity.
While the associations between recent needle practices and
HTLV-I/II-seropositivity fell short of significance, the trends in the
data were consistent with a hypothesis that HTLV-I/II is transmitted
through the sharing of injection equipment. Public health implications
of the data are discussed.
DE Adolescence Adult Aged Comparative Study Human HTLV-BLV
Infections/BLOOD/*COMPLICATIONS/VIROLOGY HTLV-I/*ISOLATION & PURIF
HTLV-II/*ISOLATION & PURIF Middle Age Racial Stocks Sex Factors
Substance Abuse, Intravenous/*COMPLICATIONS Support, U.S. Gov't, P.H.S.
JOURNAL ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).